PLoS ONE, Vol. 3, No. 7. (2008) BACKGROUND: Recently, activation-dependant structural brain plasticity in humans has been demonstrated in adults after three months of training a visio-motor skill. Learning three-ball cascade juggling was associated with a transient and highly selective increase in brain gray matter in the occipito-temporal cortex comprising the motion sensitive area hMT/V5 bilaterally. However, the exact time-scale of usage-dependant structural changes occur is still unknown. A better understanding of the temporal parameters may help to elucidate to what extent this type of cortical plasticity contributes to fast adapting cortical processes that may be relevant to learning. PRINCIPAL FINDINGS: Using a 3 Tesla scanner and monitoring whole brain structure we repeated and extended our original study in 20 healthy adult volunteers, focussing on the temporal aspects of the structural changes and investigated whether these changes are performance or exercise depen...
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Improving the Arabidopsis genome annotation using maximal transcript alignment assemblies.From: citeulike.org
Post Date: 2006-05-16 00:00:00
Nucleic Acids Res, Vol. 31, No. 19. (1 October 2003), pp. 5654-5666. The spliced alignment of expressed sequence data to genomic sequence has proven a key tool in the comprehensive annotation of genes in eukaryotic genomes. A novel algorithm was developed to assemble clusters of overlapping transcript alignments (ESTs and full-length cDNAs) into maximal alignment assemblies, thereby comprehensively incorporating all available transcript data and capturing subtle splicing varia...
more An annotation management system for relational databasesFrom: citeulike.org
Post Date: 2006-05-16 00:00:00
We present an annotation management system for relational databases. In this system, every piece of data in a relation is assumed to have zero or more annotations associated with it and annotations are propagated along, from the source to the output, as data is being transformed through a query. Such an annotation management system is important for understanding the provenance and quality of data, especially in applications that deal with integration of scientific and biological data....
more Limit on the Neutrino Mass from the WMAP Three Year DataFrom: citeulike.org
Post Date: 2006-05-16 00:00:00
We derive an upper limit on the neutrino mass from the WMAP three-year data alone by employing a deterministic minimisation method based on a grid search in multi-parameter space. Assuming the flat LCDM model with power-law adiabatic perturbations, we find the sum of m_nu < 2.0 eV in agreement with the result of the WMAP team. This result, the limit being nearly the same as that from the WMAP first-year data, means that the fundamental limit on the neutrino mass obtainable from the cosmi...
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